Factors affecting the response of lung clearance systems to acid aerosols: role of exposure concentration, exposure time, and relative acidity. | Zendy

Richard B. Schlesinger | Zendy

Open Access

Factors affecting the response of lung clearance systems to acid aerosols: role of exposure concentration, exposure time, and relative acidity.

Author(s) -

Richard B. Schlesinger

Publication year - 1989

Publication title -

environmental health perspectives

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.257

H-Index - 282

eISSN - 1552-9924

pISSN - 0091-6765

DOI - 10.1289/ehp.8979121

Subject(s) - respiratory system , aerosol , chemistry , lung , acid rain , relative humidity , environmental chemistry , homeostasis , toxicology , physiology , biology , medicine , endocrinology , meteorology , physics , organic chemistry

The ability of the lungs to clear deposited material is essential for maintenance of lung homeostasis. Acid aerosols have been shown to alter the efficiency of this process. This paper assesses the role of acid aerosol exposure concentration (C), exposure time (T), and relative acidity in producing changes in clearance from both the tracheobronchial tree and respiratory region of the lungs of rabbits. The response was found to be due to total exposure, i.e., some combination form of C x T, and was also related to relative acidity.

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