Open AccessExpression of Xenobiotic Metabolizing Enzymes in Different Lung Compartments of Smokers and Nonsmokers
Author(s) -
Thomas Thum,
Veit J. Erpenbeck,
Julia Moeller,
Jens M. Hohlfeld,
Norbert Krug,
Jürgen Borlak
Publication year - 2006
Publication title -
environmental health perspectives
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.257
H-Index - 282
eISSN - 1552-9924
pISSN - 0091-6765
DOI - 10.1289/ehp.8861
Subject(s) - xenobiotic , lung , enzyme , biology , medicine , physiology , bioinformatics , environmental health , chemistry , biochemistry
Cytochrome P450 monooxygenases (CYP) play an important role in the defense against inhaled toxicants, and expression of CYP enzymes may differ among various lung cells and tissue compartments.
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