Evidence of Genetic Effects on Blood Lead Concentration
Author(s) -
John B. Whitfield,
Veronica Dy,
Robert McQuilty,
Gu Zhu,
Grant W. Montgomery,
Manuel A. R. Ferreira,
David L. Duffy,
Michael C. Neale,
B.T. Heijmans,
Andrew C. Heath,
Nicholas G. Martin
Publication year - 2007
Publication title -
environmental health perspectives
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.257
H-Index - 282
eISSN - 1552-9924
pISSN - 0091-6765
DOI - 10.1289/ehp.8847
Subject(s) - lead poisoning , genetic variation , lead (geology) , quantitative trait locus , blood lead level , genotype , biology , lead exposure , genetics , medicine , gene , cats , paleontology , psychiatry
Lead is an environmental pollutant that causes acute and chronic toxicity. Surveys have related mean blood lead concentrations to exogenous sources, including industrial activity, use of lead-based paints, or traffic density. However, there has been little investigation of individual differences in lead absorption, distribution, or toxicity, or of genetic causes of such variation.
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