Estrogens and development. | Zendy

John A. McLachlan | Zendy; Retha R. Newbold | Zendy

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Estrogens and development.

Author(s) -

John A. McLachlan,

Retha R. Newbold

Publication year - 1987

Publication title -

environmental health perspectives

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.257

H-Index - 282

eISSN - 1552-9924

pISSN - 0091-6765

DOI - 10.1289/ehp.877525

Subject(s) - diethylstilbestrol , estrogen , hormone , sexual differentiation , biology , physiology , endocrinology , sex organ , medicine , genetics , gene

The normal development of the genital organs of mammals, including humans, is under hormonal control. A role for the female sex hormone estrogen in this process is still unclear. However, exposure of experimental animals or humans to the potent exogenous estrogen, diethylstilbestrol (DES), results in persistent differentiation effects. Since many chemicals in the environment are weakly estrogenic, the possibility of hormonally altered differentiation must be considered.

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