Ovarian neoplasia in the Sprague-Dawley rat.
Author(s) -
D. J. Lewis
Publication year - 1987
Publication title -
environmental health perspectives
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.257
H-Index - 282
eISSN - 1552-9924
pISSN - 0091-6765
DOI - 10.1289/ehp.877377
Subject(s) - histogenesis , pathology , granulosa cell , papillary tumor , mesothelioma , medicine , stroma , ovarian tumor , adenoma , clear cell , ovary , biology , carcinoma , immunohistochemistry , ovarian cancer , cancer
Macroscopic and microscopic characteristics of 210 spontaneous ovarian tumors from 7748 Sprague-Dawley rats are described. The tumors were classified as tubular adenoma, anaplastic adenocarcinoma, papillary cystadenoma, papillary cystadenocarcinoma, mesothelioma, sertoliform tubular adenoma, Sertoli's cell tumor, granulosa cell tumor, thecal cell tumor, polycystic sex cord/stromal tumor, and lipoid cell tumor. The histogenesis of the tumor types is discussed.
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