Teratological research using in vitro systems. II. Rodent limb bud culture system. | Zendy

Leonard Friedman | Zendy

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Teratological research using in vitro systems. II. Rodent limb bud culture system.

Author(s) -

Leonard Friedman

Publication year - 1987

Publication title -

environmental health perspectives

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.257

H-Index - 282

eISSN - 1552-9924

pISSN - 0091-6765

DOI - 10.1289/ehp.8772211

Subject(s) - limb bud , rodent , biology , in vitro , computer science , computational biology , bioinformatics , microbiology and biotechnology , ecology , genetics , embryo

This review represents a compilation of information related to the rodent limb bud culture system from approximately 80 publications after 1969 and conversations with workers in the field. Most of these papers and book chapters refer exclusively to studies with the mouse limb bud. Sections in this review include historical review, end point measurements, activating systems, types of compounds studied and dose response, reproducibility, statistical analysis, equipment and personnel requirements, mechanisms, and summary.

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