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Methanol extract of grain dust shows complement fixing activity and other characteristics similar to tannic acid.
Author(s) -
D.L. Skea,
I. Broder
Publication year - 1986
Publication title -
environmental health perspectives
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.257
H-Index - 282
eISSN - 1552-9924
pISSN - 0091-6765
DOI - 10.1289/ehp.8666155
Subject(s) - tannic acid , methanol , tannin , chemistry , adsorption , nuclear chemistry , biochemistry , food science , organic chemistry
We have found several similarities between tannic acid and grain dust extract prepared with methanol. Both formed a precipitate with IgG, and these interactions were inhibited by albumin. In addition, both preparations fixed complement; this activity was heat stable and was removed by prior adsorption of the preparations with hide powder. Adsorption with polyvinyl polypyrrolidone reduced the complement-fixing activity of tannic acid but not that of the methanol grain dust extract. The similarities between tannic acid and the methanol grain dust extract are consistent with the presence of a tannin or tanninlike material in grain dust.

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