Effects of inhaled acids on respiratory tract defense mechanisms. | Zendy

Richard B. Schlesinger | Zendy

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Effects of inhaled acids on respiratory tract defense mechanisms.

Author(s) -

Richard B. Schlesinger

Publication year - 1985

Publication title -

environmental health perspectives

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.257

H-Index - 282

eISSN - 1552-9924

pISSN - 0091-6765

DOI - 10.1289/ehp.856325

Subject(s) - respiratory tract , inhalation , respiratory system , pulmonary disease , medicine , defence mechanisms , respiratory tract infections , immunology , chemistry , physiology , pharmacology , biochemistry , anesthesia , gene

The respiratory tract is endowed with an interlocking array of nonspecific and specific defense mechanisms which protect it from the effects of inhaled microbes and toxicants, and reduce the risk of absorption of materials into the bloodstream, with subsequent systemic translocation. Ambient acids may compromise these defenses, perhaps providing a link between exposure and development of chronic and acute pulmonary disease. This paper reviews the effects of inhaled acids upon the nonspecific clearance system of the lungs.

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