Induction of Inflammation in Vascular Endothelial Cells by Metal Oxide Nanoparticles: Effect of Particle Composition
Author(s) -
Andrea Gojová,
Bing Guo,
Rama S. Kota,
John C. Rutledge,
Ian M. Kennedy,
Abdul I. Barakat
Publication year - 2006
Publication title -
environmental health perspectives
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.257
H-Index - 282
eISSN - 1552-9924
pISSN - 0091-6765
DOI - 10.1289/ehp.8497
Subject(s) - inflammation , composition (language) , metal , particle (ecology) , chemistry , nanoparticle , immunology , medicine , biology , materials science , nanotechnology , ecology , linguistics , philosophy , organic chemistry
The mechanisms governing the correlation between exposure to ultrafine particles and the increased incidence of cardiovascular disease remain unknown. Ultrafine particles appear to cross the pulmonary epithelial barrier into the bloodstream, raising the possibility of direct contact with the vascular endothelium.
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