Acute and subchronic toxicity of ethylene glycol monobutyl ether. | Zendy

T. R. Tyler | Zendy

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Acute and subchronic toxicity of ethylene glycol monobutyl ether.

Author(s) -

T. R. Tyler

Publication year - 1984

Publication title -

environmental health perspectives

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.257

H-Index - 282

eISSN - 1552-9924

pISSN - 0091-6765

DOI - 10.1289/ehp.8457185

Subject(s) - ethylene glycol , toxicity , acute toxicity , ether , toxicology , chemistry , animal studies , adverse effect , acute exposure , medicine , pharmacology , organic chemistry , biology

The available information on the acute and subchronic toxicity of ethylene glycol monobutyl ether is reviewed. Data from animal studies have been examined from the standpoint of dose-response relationships and the sensitivity of various animal species, including man, to the effects of this chemical. In view of recent findings with other chemically related glycol ethers, particular attention has been given to possible adverse effects on blood and testicular tissue. In evaluating the hazard that this chemical may pose to man, consideration has been given to likely routes of exposure and its irritant properties. It is concluded that the available information continues to support the current ACGIH TWA8-TLV of 25 ppm with a STEL of 75 ppm.

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