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Physiological basis and interpretation of indices of pulmonary mechanics.
Author(s) -
Jeffrey M. Drazen
Publication year - 1984
Publication title -
environmental health perspectives
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.257
H-Index - 282
eISSN - 1552-9924
pISSN - 0091-6765
DOI - 10.1289/ehp.84563
Subject(s) - parenchyma , pulmonary function testing , pulmonary compliance , lung function , respiratory physiology , lung , medicine , intensive care medicine , pathology
Tests of pulmonary mechanical function provide information about the state of the lungs, both airways and parenchyma. This information can be extracted from measurements made in experimental animals, especially the combined determination of pulmonary resistance and dynamic compliance. This report discusses the rationale upon which effects of an intervention on the lung periphery can be distinguished from those on more central airways. Further, practical considerations involved in making these measurements are discussed.

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