Crystals of cadmium, zinc metallothionein. | Zendy

K A Melis | Zendy; D C Carter | Zendy; C.D. Stout | Zendy; Dennis R. Winge | Zendy

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Crystals of cadmium, zinc metallothionein.

Author(s) -

K A Melis,

D C Carter,

C.D. Stout,

Dennis R. Winge

Publication year - 1984

Publication title -

environmental health perspectives

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.257

H-Index - 282

eISSN - 1552-9924

pISSN - 0091-6765

DOI - 10.1289/ehp.8454105

Subject(s) - metallothionein , zinc , cadmium , tetragonal crystal system , crystallography , chemistry , molecule , crystal structure , crystal (programming language) , organic chemistry , computer science , programming language

Single crystals have been grown of Cd,Zn metallothionein isoform II from rat liver. The space group is P41212(P43212) with unit cell dimensions a = b = 31.0 A and c = 120.0 A, and one molecule in the crystallographic asymmetric unit. The crystals are square bipyramids elongated on the tetragonal c-axis and are grown by repetitive seeding. The crystals are suitable for high resolution structure analysis. Assays of dissolved crystals show that the crystals have the same Cd and Zn content and amino acid composition as the native, as-isolated protein.

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