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Some historical aspects of N-aryl carcinogens and their metabolic activation.
Author(s) -
James A. Miller,
Elizabeth C. Miller
Publication year - 1983
Publication title -
environmental health perspectives
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.257
H-Index - 282
eISSN - 1552-9924
pISSN - 0091-6765
DOI - 10.1289/ehp.83493
Subject(s) - carcinogen , carcinogenesis , aryl , function (biology) , toxicology , medicine , chemistry , biology , cancer , biochemistry , genetics , organic chemistry , alkyl
This limited review of the early studies on the activation of the N-aryl carcinogens was written to provide a background for the current research to be presented at this conference on carcinogenesis by N-aryl compounds. Since the work of the past 10 years is too recent to be judged in a historical sense and because those data are much better known by current investigators, this review is generally limited to data up to 1972.

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