Brief overview of selected aspects of testicular hormone action. | Zendy

Leslie P. Bullock | Zendy

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Brief overview of selected aspects of testicular hormone action.

Author(s) -

Leslie P. Bullock

Publication year - 1981

Publication title -

environmental health perspectives

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.257

H-Index - 282

eISSN - 1552-9924

pISSN - 0091-6765

DOI - 10.1289/ehp.813811

Subject(s) - androgen receptor , androgen , mechanism of action , action (physics) , hormone , nuclear receptor , receptor , biology , endocrinology , medicine , biochemistry , prostate cancer , transcription factor , in vitro , physics , cancer , quantum mechanics , gene

This paper is designed to give an overview of the mechanism of androgen action and some of the factors that can affect it. The discussion of androgen action includes androgen transport in the blood, metabolism, receptor binding, nuclear activation and selected aspects of biological response. The importance of recognizing interspecies and interstrain differences in specific aspects of androgen action is mentioned. Some examples of the effects of environmental agents on androgen metabolism, receptor binding and biological response are included.

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