Protein abnormalities in macrophages bearing asbestos.
Author(s) -
P.F. Lemkin,
Lewis E. Lipkin,
C R Merril,
Sidney Shifrin
Publication year - 1980
Publication title -
environmental health perspectives
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.257
H-Index - 282
eISSN - 1552-9924
pISSN - 0091-6765
DOI - 10.1289/ehp.803475
Subject(s) - phagocytosis , asbestos , macrophage , chemistry , asbestosis , biochemistry , immunology , microbiology and biotechnology , pathology , biology , medicine , materials science , in vitro , metallurgy
Computerized techniques for the evaluation of O'Farrell two-dimensional electrophoretic gels have been applied to proteins derived from asbestos bearing macrophages. Preliminary results indicate definite changes in the protein content of cells depending on fiber phagocytosis.
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