Critical periods for behavioral anomalies in mice. | Zendy

Patricia M. Rodier | Zendy

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Critical periods for behavioral anomalies in mice.

Author(s) -

Patricia M. Rodier

Publication year - 1976

Publication title -

environmental health perspectives

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.257

H-Index - 282

eISSN - 1552-9924

pISSN - 0091-6765

DOI - 10.1289/ehp.761879

Subject(s) - teratology , neuroscience , biology , physiology , toxicology , genetics , fetus , pregnancy

While mice have been used less frequently than rats in behavioral research, there use has some advantages in teratological studies. The development of the mouse CNS has been investigated more extensively than that of the rat. Since time of insult has been found to be an important factor in effects on both anatomy and behavior, data on the sequence of events in CNS development are valuable in planning and interpreting behavioral assessments of potential teratogens. A comparison of studies in mice and rats suggests that behavioral effects of teratogens are similar in the two species and demonstrates that mice can be used successfully in a variety of behavioral evaluations.

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