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Physiologic basis and interpretation of common indices of respiratory mechanical function.
Author(s) -
Jeffrey M. Drazen
Publication year - 1976
Publication title -
environmental health perspectives
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.257
H-Index - 282
eISSN - 1552-9924
pISSN - 0091-6765
DOI - 10.1289/ehp.761611
Subject(s) - airway resistance , pulmonary compliance , respiratory system , compliance (psychology) , pulmonary function testing , lung , airway , medicine , respiratory physiology , lung function , mechanical resistance , parenchyma , cardiology , intensive care medicine , pathology , anesthesia , psychology , materials science , social psychology , composite material
Tests of pulmonary mechanical function may be used in determining the prominent site of pulmonary reaction to intervention. Responses may be localized from a knowledge of changes in lung resistance and compliance. A peripheral airway or parenchymal response is characterized by a decrease in lung compliance. A central airway reaction is characterized by an increase in pulmonary resistance. In mixed reactions both parameters may change. In this communication some of the physiologic determinants of pulmonary resistance and compliance are discussed and examples of localized responses given.

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