Determination of human body burden baseline date of platinum through autopsy tissue analysis.
Author(s) -
F Vandiver,
F V Duffield,
Anna M. Yoakum,
Jacob R. Bumgarner,
Jonathan Moran
Publication year - 1976
Publication title -
environmental health perspectives
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.257
H-Index - 282
eISSN - 1552-9924
pISSN - 0091-6765
DOI - 10.1289/ehp.7615131
Subject(s) - platinum , autopsy , baseline (sea) , pathology , medicine , chemistry , biology , catalysis , biochemistry , fishery
Results of analysis for platinum in 97 autopsy sets are presented. Analysis was performed by a specially developed emission spectrochemical method. Almost half of the individuals studied were found to have detectable platinum in one or more tissue samples. Platinum was found to be deposited in 13 of 21 tissue types investigated. Surprisingly high values were observed in subcutaneous fat, previously not considered to be a target site for platinum deposition. These data will serve as a human tissue platinum burden baseline in EPA's Catalyst Research Program.
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