Concentration--time relationship for various regimens of inhalation of organic compounds. | Zendy

Г И Сидоренко | Zendy; М. А. Пинигин | Zendy

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Concentration--time relationship for various regimens of inhalation of organic compounds.

Author(s) -

Г И Сидоренко,

М. А. Пинигин

Publication year - 1976

Publication title -

environmental health perspectives

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.257

H-Index - 282

eISSN - 1552-9924

pISSN - 0091-6765

DOI - 10.1289/ehp.761317

Subject(s) - inhalation , inhalation exposure , environmental chemistry , toxicity , toxicology , logarithm , acute toxicity , chemistry , environmental science , physiology , pharmacology , medicine , anesthesia , biology , mathematics , organic chemistry , mathematical analysis

An attempt was made to establish a concentration--time relationship for continuous and interrupted inhalation of a number of nonelectrolytes to establish norms for the permissible content of harmful substances in atmospheric air. The tests showed that the indicated relationship can be expressed in the form of a straight line on a logarithmic grid by using either acute toxicity parameters or the onset of physiological and biochemical shifts. This makes it possible to predict the chronic effect thresholds of substances on the basis of the results of short-term experiments.

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