Epidemiology of toluene diisocyanate (TDI)-induced respiratory disease. | Zendy

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Epidemiology of toluene diisocyanate (TDI)-induced respiratory disease.

Author(s) -

John Peters,

David H. Wegman

Publication year - 1975

Publication title -

environmental health perspectives

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.257

H-Index - 282

eISSN - 1552-9924

pISSN - 0091-6765

DOI - 10.1289/ehp.751197

Subject(s) - toluene diisocyanate , respiratory system , irritation , sensitization , medicine , pulmonary function testing , respiratory disease , intensive care medicine , immunology , lung , chemistry , organic chemistry , polyurethane

This paper describes our experience with the respiratory effects of TDI. Five respiratory reactions attributable to TDI are described with supporting evidence. The reactions are sensitization, irritation from overexposure, acute loss of ventilatory capacity, accelerated loss of pulmonary function and induction of a general asthmatic state. Evidence is presented that suggests a safe exposure level.

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