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Penetration of cells by asbestos fibers
Author(s) -
J. Michael Davis,
Robert Bolton,
John Garrett
Publication year - 1974
Publication title -
environmental health perspectives
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.257
H-Index - 282
eISSN - 1552-9924
pISSN - 0091-6765
DOI - 10.1289/ehp.749255
Subject(s) - asbestos , penetration (warfare) , asbestos fibers , phagocytosis , ingestion , chemistry , microbiology and biotechnology , materials science , biology , composite material , biochemistry , operations research , engineering
Studies on the behavior of asbestos fibers within tissues have shown that the only cells that regularly contain asbestos are macrophages and their derivatives. However, these cells actively incorporate the asbestos fibers by the process of phagocytosis, and there is little evidence of direct penetration. Examination of the gut lining after prolonged asbestos ingestion has shown no evidence of dust penetration either through or between the epithelial cells. The structure and arrangement of these cells is discussed, and it is suggested that they are exceptionally well adapted to prevent penetration by any solid material.

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