Commentary: penetration of asbestos through the digestive wall in rats | Zendy

R. D. Pontefract | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Commentary: penetration of asbestos through the digestive wall in rats

Author(s) -

R. D. Pontefract

Publication year - 1974

Publication title -

environmental health perspectives

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.257

H-Index - 282

eISSN - 1552-9924

pISSN - 0091-6765

DOI - 10.1289/ehp.749213

Subject(s) - spleen , stomach , lung , asbestos , pathology , chrysotile , electron microscope , small intestine , chemistry , biology , medicine , materials science , physics , optics , metallurgy

Distribution studies on asbestos fibers administered to rats were performed with the electron microscope and were supplemented with studies involving use of tritiated and neutron-activated asbestos. Chrysotile filbers were injected into the stomach of rats, and 2–4 days later various tissues were solubilized and their fiber content studied. Fibers were isolated from the blood, spleen, omentum, and brain of the treated rats. Highest levels of orally administered fibers decreased within 24 hr in the blood, lung, and spleen; the count remained high in tissues such as the omentum and brain.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research