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The Science and Practice of Carcinogen Identification and Evaluation
Author(s) -
Vincent James Cogliano,
Robert A. Baan,
Kurt Straíf,
Yann Grosse,
Béatrice Secretan,
Fatiha El Ghissassi,
Paul Kleihues
Publication year - 2004
Publication title -
environmental health perspectives
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.257
H-Index - 282
eISSN - 1552-9924
pISSN - 0091-6765
DOI - 10.1289/ehp.6950
Subject(s) - identification (biology) , carcinogen , international agency , environmental health , medicine , biology , botany , genetics
Several national and international health agencies have established programs with the aim of identifying agents and exposures that cause cancer in humans. Carcinogen identification is an activity grounded in the scientific evaluation of the results of human epidemiologic studies, long-term bioassays in experimental animals, and other data relevant to an evaluation of carcinogenicity and its mechanisms. In this commentary, after a brief discussion of the science basis common to the evaluation of carcinogens across different programs, we discuss in more detail the principles and procedures currently used by the IARC Monographs program.

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