Use of QSARs in international decision-making frameworks to predict ecologic effects and environmental fate of chemical substances. | Zendy

Mark T.D. Cronin | Zendy; John D. Walker | Zendy; Joanna Jaworska | Zendy; Michael Comber | Zendy; Christopher D Watts | Zendy; Andrew Worth | Zendy

Open Access

Use of QSARs in international decision-making frameworks to predict ecologic effects and environmental fate of chemical substances.

Author(s) -

Mark T.D. Cronin,

John D. Walker,

Joanna Jaworska,

Michael Comber,

Christopher D Watts,

Andrew Worth

Publication year - 2003

Publication title -

environmental health perspectives

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.257

H-Index - 282

eISSN - 1552-9924

pISSN - 0091-6765

DOI - 10.1289/ehp.5759

Subject(s) - agency (philosophy) , organic chemicals , environmental toxicology , quantitative structure–activity relationship , environmental regulation , environmental planning , environmental science , environmental resource management , environmental chemistry , chemistry , biology , bioinformatics , philosophy , organic chemistry , epistemology , toxicity

This article is a review of the use, by regulatory agencies and authorities, of quantitative structure-activity relationships (QSARs) to predict ecologic effects and environmental fate of chemicals. For many years, the U.S. Environmental Protection Agency has been the most prominent regulatory agency using QSARs to predict the ecologic effects and environmental fate of chemicals. However, as increasing numbers of standard QSAR methods are developed and validated to predict ecologic effects and environmental fate of chemicals, it is anticipated that more regulatory agencies and authorities will find them to be acceptable alternatives to chemical testing.

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