Epigenome-Wide Assessment of DNA Methylation in the Placenta and Arsenic Exposure in the New Hampshire Birth Cohort Study (USA)
Author(s) -
Benjamin B. Green,
Margaret R. Karagas,
Tracy Punshon,
Brian P. Jackson,
David J. Robbins,
E. Andrés Houseman,
Carmen J. Marsit
Publication year - 2016
Publication title -
environmental health perspectives
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.257
H-Index - 282
eISSN - 1552-9924
pISSN - 0091-6765
DOI - 10.1289/ehp.1510437
Subject(s) - dna methylation , methylation , cpg site , epigenome , arsenic , biology , placenta , offspring , andrology , population , physiology , pregnancy , genetics , medicine , fetus , gene , chemistry , gene expression , environmental health , organic chemistry
Arsenic is one of the most commonly encountered environmental toxicants, and research from model systems has suggested that one mode of its toxic activity may be through alterations in DNA methylation. In utero exposure to arsenic can affect fetal, newborn, and infant health, resulting in a range of phenotypic outcomes.
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