Systems Toxicology of Male Reproductive Development: Profiling 774 Chemicals for Molecular Targets and Adverse Outcomes | Zendy

Maxwell C. K. Leung | Zendy; Jimmy Phuong | Zendy; Nancy Baker | Zendy; Nisha S. Sipes | Zendy; Gary Klinefelter | Zendy; Matthew T. Martin | Zendy; Keith W. McLaurin | Zendy; R. Woodrow Setzer | Zendy; Sally D. Perreault | Zendy; Richard Judson | Zendy; Thomas B. Knudsen | Zendy

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Systems Toxicology of Male Reproductive Development: Profiling 774 Chemicals for Molecular Targets and Adverse Outcomes

Author(s) -

Maxwell C. K. Leung,

Jimmy Phuong,

Nancy Baker,

Nisha S. Sipes,

Gary Klinefelter,

Matthew T. Martin,

Keith W. McLaurin,

R. Woodrow Setzer,

Sally D. Perreault,

Richard Judson,

Thomas B. Knudsen

Publication year - 2015

Publication title -

environmental health perspectives

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.257

H-Index - 282

eISSN - 1552-9924

pISSN - 0091-6765

DOI - 10.1289/ehp.1510385

Subject(s) - biology , semen quality , adverse outcome pathway , reproductive toxicity , adverse effect , developmental toxicity , sperm , physiology , bioinformatics , genetics , toxicity , computational biology , pharmacology , medicine , fetus , pregnancy

Trends in male reproductive health have been reported for increased rates of testicular germ cell tumors, low semen quality, cryptorchidism, and hypospadias, which have been associated with prenatal environmental chemical exposure based on human and animal studies.

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