On the Utility of ToxCast™ and ToxPi as Methods for Identifying New Obesogens
Author(s) -
Amanda Janesick,
Giorgio Dimastrogiovanni,
Lenka Vanek,
Christy Boulos,
Raquel Chamorro-García,
Weiyi Tang,
Bruce Blumberg
Publication year - 2016
Publication title -
environmental health perspectives
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.257
H-Index - 282
eISSN - 1552-9924
pISSN - 0091-6765
DOI - 10.1289/ehp.1510352
Subject(s) - adipogenesis , peroxisome proliferator activated receptor , biology , biochemistry , mesenchymal stem cell , microbiology and biotechnology , receptor
In ToxCast™ Phase I, the U.S. EPA commissioned screening of 320 pesticides, herbicides, fungicides, and other chemicals in a series of high-throughput assays. The agency also developed a toxicological prioritization tool, ToxPi, to facilitate using ToxCast™ assays to predict biological function.
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