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Prenatal Exposure to Phthalates and Anogenital Distance in Male Infants from a Low-Exposed Danish Cohort (2010–2012)
Author(s) -
Tina Kold Jensen,
Hanne Frederiksen,
Henriette Boye Kyhl,
Tina Harmer Lassen,
Shanna H. Swan,
CarlGustaf Bornehag,
Niels E. Skakkebæk,
Katharina M. Main,
Dorte Vesterholm Lind,
Steffen Husby,
AnnaMaria Andersson
Publication year - 2015
Publication title -
environmental health perspectives
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.257
H-Index - 282
eISSN - 1552-9924
pISSN - 0091-6765
DOI - 10.1289/ehp.1509870
Subject(s) - anogenital distance , phthalate , medicine , offspring , pregnancy , quartile , cohort , population , cohort study , gestation , physiology , obstetrics , confidence interval , biology , environmental health , chemistry , in utero , fetus , genetics , organic chemistry
Phthalates comprise a large class of chemicals used in a variety of consumer products. Several have anti-androgenic properties, and in rodents prenatal exposure has been associated with reduced anogenital distance (AGD)-the distance from the anus to the genitals in male offspring. Few human studies have been conducted, but associations between the anti-androgenic phthalates and male AGD have been reported.

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