Thyroid Antagonists (Perchlorate, Thiocyanate, and Nitrate) and Childhood Growth in a Longitudinal Study of U.S. Girls
Author(s) -
Nancy Mervish,
Ashley Pajak,
Susan L. Teitelbaum,
Susan M. Pinney,
Gayle C. Windham,
Lawrence H. Kushi,
Frank M. Biro,
Liza Valentín-Blasini,
Benjamin C. Blount,
Mary S. Wolff
Publication year - 2015
Publication title -
environmental health perspectives
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.257
H-Index - 282
eISSN - 1552-9924
pISSN - 0091-6765
DOI - 10.1289/ehp.1409309
Subject(s) - perchlorate , thiocyanate , thyroid , nitrate , medicine , longitudinal study , thyroid hormones , endocrinology , chemistry , pediatrics , biochemistry , pathology , organic chemistry , ion
Perchlorate, thiocyanate, and nitrate are sodium/iodide symporter (NIS) inhibitors that block iodide uptake into the thyroid, thus affecting thyroid function. Thyroid dysfunction can adversely affect somatic growth and development in children. To our knowledge, no studies have examined effects of NIS inhibitors on body size measures.
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