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Effects of Low-Dose Bisphenol A on DNA Damage and Proliferation of Breast Cells: The Role of c-Myc
Author(s) -
Daniella Pfeifer,
YoungMin Chung,
Mickey C.T. Hu
Publication year - 2015
Publication title -
environmental health perspectives
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.257
H-Index - 282
eISSN - 1552-9924
pISSN - 0091-6765
DOI - 10.1289/ehp.1409199
Subject(s) - dna damage , gene silencing , cell growth , comet assay , mammary gland , cell cycle , estrogen receptor , cancer research , biology , cell , bisphenol a , chemistry , microbiology and biotechnology , dna , gene , biochemistry , cancer , genetics , breast cancer , organic chemistry , epoxy
Humans are exposed to low-dose bisphenol A (BPA) through plastic consumer products and dental sealants containing BPA. Although a number of studies have investigated the mammary gland effects after high-dose BPA exposure, the study findings differ. Furthermore, there has been a lack of mechanistic studies.

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