Characterization of Conserved Toxicogenomic Responses in Chemically Exposed Hepatocytes across Species and Platforms | Zendy

Nehmé El-Hachem | Zendy; Patrick Großmann | Zendy; Alexis Blanchet-Cohen | Zendy; Alain R. Bateman | Zendy; Nicolas Bouchard | Zendy; Jacques Archambault | Zendy; Hugo J.W.L. Aerts | Zendy; Benjamin HaibeKains | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Characterization of Conserved Toxicogenomic Responses in Chemically Exposed Hepatocytes across Species and Platforms

Author(s) -

Nehmé El-Hachem,

Patrick Großmann,

Alexis Blanchet-Cohen,

Alain R. Bateman,

Nicolas Bouchard,

Jacques Archambault,

Hugo J.W.L. Aerts,

Benjamin HaibeKains

Publication year - 2015

Publication title -

environmental health perspectives

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.257

H-Index - 282

eISSN - 1552-9924

pISSN - 0091-6765

DOI - 10.1289/ehp.1409157

Subject(s) - toxicogenomics , biology , transcriptome , computational biology , gene expression profiling , in vivo , adverse outcome pathway , microbiology and biotechnology , signal transduction , in vitro toxicology , gene expression , gene , genetics

Genome-wide expression profiling is increasingly being used to identify transcriptional changes induced by drugs and environmental stressors. In this context, the Toxicogenomics Project-Genomics Assisted Toxicity Evaluation system (TG-GATEs) project generated transcriptional profiles from rat liver samples and human/rat cultured primary hepatocytes exposed to more than 100 different chemicals.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research