Biased Exposure–Health Effect Estimates from Selection in Cohort Studies: Are Environmental Studies at Particular Risk?
Author(s) -
Marc G. Weisskopf,
David Sparrow,
Howard Hu,
Melinda C. Power
Publication year - 2015
Publication title -
environmental health perspectives
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.257
H-Index - 282
eISSN - 1552-9924
pISSN - 0091-6765
DOI - 10.1289/ehp.1408888
Subject(s) - hazard ratio , medicine , confounding , selection bias , proportional hazards model , confidence interval , cohort , cohort study , environmental health , demography , information bias , inverse probability weighting , propensity score matching , pathology , sociology
The process of creating a cohort or cohort substudy may induce misleading exposure-health effect associations through collider stratification bias (i.e., selection bias) or bias due to conditioning on an intermediate. Studies of environmental risk factors may be at particular risk.
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