Effects of Benzo[ a ]pyrene Exposure on Human Hepatocellular Carcinoma Cell Angiogenesis, Metastasis, and NF- κ B Signaling
Author(s) -
Qian Ba,
Junyang Li,
Chao Huang,
Hongling Qiu,
Jingquan Li,
Ruiai Chu,
Wei Zhang,
Dong Xie,
Yongning Wu,
Hui Wang
Publication year - 2014
Publication title -
environmental health perspectives
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.257
H-Index - 282
eISSN - 1552-9924
pISSN - 0091-6765
DOI - 10.1289/ehp.1408524
Subject(s) - angiogenesis , metastasis , cancer research , in vivo , hepatocellular carcinoma , benzo(a)pyrene , nf κb , cell growth , carcinogen , cancer , medicine , biology , immunology , inflammation , biochemistry , microbiology and biotechnology
Benzo[a]pyrene (B[a]P) is a common environmental and foodborne pollutant. Although the carcinogenicity of high-dose B[a]P has been extensively reported, the effects of long-term B[a]P exposure at lower environmental doses on cancer development are less understood.
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