Characterizing the Peroxisome Proliferator-Activated Receptor (PPAR γ ) Ligand Binding Potential of Several Major Flame Retardants, Their Metabolites, and Chemical Mixtures in House Dust | Zendy

Mingliang Fang | Zendy; Thomas F. Webster | Zendy; P. Lee Ferguson | Zendy; Heather M. Stapleton | Zendy

Open Access

Characterizing the Peroxisome Proliferator-Activated Receptor (PPAR γ ) Ligand Binding Potential of Several Major Flame Retardants, Their Metabolites, and Chemical Mixtures in House Dust

Author(s) -

Mingliang Fang,

Thomas F. Webster,

P. Lee Ferguson,

Heather M. Stapleton

Publication year - 2014

Publication title -

environmental health perspectives

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.257

H-Index - 282

eISSN - 1552-9924

pISSN - 0091-6765

DOI - 10.1289/ehp.1408522

Subject(s) - chemistry , potency , peroxisome proliferator activated receptor , ligand (biochemistry) , receptor , environmental chemistry , binding site , metabolite , biochemistry , in vitro

Accumulating evidence has shown that some environmental contaminants can alter adipogenesis and act as obesogens. Many of these contaminants act via the activation of the peroxisome proliferator-activated receptor γ (PPARγ) nuclear receptor.

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