The Blood Exposome and Its Role in Discovering Causes of Disease | Zendy

Stephen M. Rappaport | Zendy; Dinesh Kumar Barupal | Zendy; David S. Wishart | Zendy; Paolo Vineis | Zendy; Augustin Scalbert | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

The Blood Exposome and Its Role in Discovering Causes of Disease

Author(s) -

Stephen M. Rappaport,

Dinesh Kumar Barupal,

David S. Wishart,

Paolo Vineis,

Augustin Scalbert

Publication year - 2014

Publication title -

environmental health perspectives

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.257

H-Index - 282

eISSN - 1552-9924

pISSN - 0091-6765

DOI - 10.1289/ehp.1308015

Subject(s) - exposome , disease , biology , human blood , computational biology , medicine , physiology , bioinformatics , environmental health , pathology

Since 2001, researchers have examined the human genome (G) mainly to discover causes of disease, despite evidence that G explains relatively little risk. We posit that unexplained disease risks are caused by the exposome (E; representing all exposures) and G × E interactions. Thus, etiologic research has been hampered by scientists' continuing reliance on low-tech methods to characterize E compared with high-tech omics for characterizing G.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research