Identification of DNA Methylation Changes in Newborns Related to Maternal Smoking during Pregnancy
Author(s) -
Christina A. Markunas,
Zongli Xu,
Sophia Harlid,
Paul A. Wade,
Rolv T. Lie,
Jack A. Taylor,
Allen J. Wilcox
Publication year - 2014
Publication title -
environmental health perspectives
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.257
H-Index - 282
eISSN - 1552-9924
pISSN - 0091-6765
DOI - 10.1289/ehp.1307892
Subject(s) - dna methylation , epigenetics , methylation , pregnancy , epigenome , cpg site , cotinine , nicotine , tobacco smoke , medicine , physiology , biology , bioinformatics , genetics , gene , gene expression , environmental health
Maternal smoking during pregnancy is associated with significant infant morbidity and mortality, and may influence later disease risk. One mechanism by which smoking (and other environmental factors) might have long-lasting effects is through epigenetic modifications such as DNA methylation.
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