Open AccessBeyond the Mean: Quantile Regression to Explore the Association of Air Pollution with Gene-Specific Methylation in the Normative Aging Study
Author(s) -
MarieAbèle Bind,
Brent A. Coull,
Annette Peters,
Andrea Baccarelli,
Letizia Tarantini,
Laura Cantone,
Pantel Vokonas,
Petros Koutrakis,
Joel Schwartz
Publication year - 2015
Publication title -
environmental health perspectives
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.257
H-Index - 282
eISSN - 1552-9924
pISSN - 0091-6765
DOI - 10.1289/ehp.1307824
Subject(s) - dna methylation , methylation , interquartile range , epigenetics , biology , medicine , genetics , gene expression , gene
Air pollution has been related to mean changes in outcomes, including DNA methylation. However, mean regression analyses may not capture associations that occur primarily in the tails of the outcome distribution.
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