Open AccessChronic Arsenic Exposure and Angiogenesis in Human Bronchial Epithelial Cells via the ROS/miR-199a-5p/HIF-1 α /COX-2 Pathway
Author(s) -
Jun He,
Min Wang,
Yue Jiang,
Qiudan Chen,
Shaohua Xu,
Qing Xu,
BingHua Jiang,
Liu L
Publication year - 2014
Publication title -
environmental health perspectives
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.257
H-Index - 282
eISSN - 1552-9924
pISSN - 0091-6765
DOI - 10.1289/ehp.1307545
Subject(s) - angiogenesis , carcinogenesis , cancer research , arsenic , carcinogen , chorioallantoic membrane , chemistry , in vivo , biology , cancer , biochemistry , genetics , organic chemistry
Environmental and occupational exposure to arsenic is a major public health concern. Although it has been identified as a human carcinogen, the molecular mechanism underlying the arsenic-induced carcinogenesis is not well understood.
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