Open AccessModulation of Distinct Asthmatic Phenotypes in Mice by Dose-Dependent Inhalation of Microbial Products
Author(s) -
Gregory S. Whitehead,
Seddon Y. Thomas,
Donald N. Cook
Publication year - 2013
Publication title -
environmental health perspectives
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.257
H-Index - 282
eISSN - 1552-9924
pISSN - 0091-6765
DOI - 10.1289/ehp.1307280
Subject(s) - neutrophilia , immunology , ovalbumin , lipopolysaccharide , eosinophilia , sensitization , medicine , asthma , inhalation , cytokine , inflammation , allergen , pulmonary eosinophilia , allergy , immune system , eosinophil , anatomy
Humans with asthma display considerable heterogeneity with regard to T helper (Th) 2-associated eosinophilic and Th17-associated neutrophilic inflammation, but the impact of the environment on these different forms of asthma is poorly understood.
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