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The Human Early-Life Exposome (HELIX): Project Rationale and Design
Author(s) -
Martine Vrijheid,
Rémy Slama,
Oliver Robinson,
Leda Chatzi,
Muireann Coen,
Peter van den Hazel,
Cathrine Thomsen,
John Wright,
Toby J. Athersuch,
Narcís Avellana,
Xavier Basagaña,
Céline Brochot,
Luca Bucchini,
Mariona Bustamante,
Ángel Carracedo,
Maribel Casas,
Xavier Estivill,
Lesley Fairley,
Diana van Gent,
Juan R. González,
Berit Granum,
Regina Gražulevicˇiene ̇,
Kristine B. Gützkow,
Jordi Júlvez,
Hector C. Keun,
Manolis Kogevinas,
Rosemary McEachan,
Helle Margrete Meltzer,
Eduard Sabidó,
Per E. Schwarze,
Valérie Siroux,
Jordi Sunyer,
Elizabeth J. Want,
Florence Zeman,
Mark Nieuwenhuijsen
Publication year - 2014
Publication title -
environmental health perspectives
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.257
H-Index - 282
eISSN - 1552-9924
pISSN - 0091-6765
DOI - 10.1289/ehp.1307204
Subject(s) - exposome , medicine , computational biology , bioinformatics , biology , environmental health
Developmental periods in early life may be particularly vulnerable to impacts of environmental exposures. Human research on this topic has generally focused on single exposure-health effect relationships. The "exposome" concept encompasses the totality of exposures from conception onward, complementing the genome.

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