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Association between Maternal Serum Perfluoroalkyl Substances during Pregnancy and Maternal and Cord Thyroid Hormones: Taiwan Maternal and Infant Cohort Study
Author(s) -
Yan Wang,
Walter J. Rogan,
PauChung Chen,
GuangWen Lien,
Hsiao-Yen Chen,
Ying-Chih Tseng,
Matthew P. Longnecker,
ShuLi Wang
Publication year - 2014
Publication title -
environmental health perspectives
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.257
H-Index - 282
eISSN - 1552-9924
pISSN - 0091-6765
DOI - 10.1289/ehp.1306925
Subject(s) - hormone , pregnancy , thyroid , medicine , endocrinology , fetus , triiodothyronine , physiology , biology , genetics
Perfluoroalkyl substances (PFASs) are synthetic compounds that are widely used in industry and are often detectable in humans. In pregnant rats and their pups, PFASs can interfere with thyroid hormone homeostasis. In humans, maternal thyroid hormones supply the fetus throughout pregnancy, and thyroid hormones play a critical role in fetal growth and neurodevelopment.

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