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Air Pollution–Mediated Susceptibility to Inflammation and Insulin Resistance: Influence of CCR2 Pathways in Mice
Author(s) -
Cuiqing Liu,
Xiaohua Xu,
Yuntao Bai,
Tse-Yao Wang,
Xiaoquan Rao,
Aixia Wang,
Lixian Sun,
Zhekang Ying,
Liubov V. Gushchina,
Andrei Maiseyeu,
Masako Morishita,
Qinghua Sun,
Jack R. Harkema,
Sanjay Rajagopalan
Publication year - 2013
Publication title -
environmental health perspectives
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.257
H-Index - 282
eISSN - 1552-9924
pISSN - 0091-6765
DOI - 10.1289/ehp.1306841
Subject(s) - insulin resistance , ccr2 , medicine , endocrinology , adipose tissue , inflammation , insulin receptor , biology , insulin , chemokine , chemokine receptor
Epidemiologic and experimental studies support an association between PM2.5 exposure and insulin resistance (IR). Innate immune cell activation has been suggested to play a role in the pathogenesis of these effects.

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