Perinatally Administered Bisphenol A as a Potential Mammary Gland Carcinogen in Rats | Zendy

Nicole Acevedo | Zendy; Barbara J. Davis | Zendy; Cheryl M. Schaeberle | Zendy; Carlos Sonnenschein | Zendy; Ana M. Soto | Zendy

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Perinatally Administered Bisphenol A as a Potential Mammary Gland Carcinogen in Rats

Author(s) -

Nicole Acevedo,

Barbara J. Davis,

Cheryl M. Schaeberle,

Carlos Sonnenschein,

Ana M. Soto

Publication year - 2013

Publication title -

environmental health perspectives

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.257

H-Index - 282

eISSN - 1552-9924

pISSN - 0091-6765

DOI - 10.1289/ehp.1306734

Subject(s) - offspring , gestation , lactation , mammary gland , endocrinology , medicine , fetus , pregnancy , biology , carcinogen , endocrine disruptor , physiology , endocrine system , hormone , cancer , breast cancer , genetics

Environmental exposure to bisphenol A (BPA) affects mammary gland development in rodents and primates. Prenatal exposure to environmentally relevant doses of BPA increased the number of intraductal hyperplasias and ductal carcinomas in situ by 50 days of age in Wistar-Furth rats.

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