AhR-Mediated Effects of Dioxin on Neuronal Acetylcholinesterase Expression in Vitro | Zendy

Heidi Qunhui Xie | Zendy; Haiming Xu | Zendy; Hualing Fu | Zendy; Qin Hu | Zendy; Wenjing Tian | Zendy; Xinhui Pei | Zendy; Bin Zhao | Zendy

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AhR-Mediated Effects of Dioxin on Neuronal Acetylcholinesterase Expression in Vitro

Author(s) -

Heidi Qunhui Xie,

Haiming Xu,

Hualing Fu,

Qin Hu,

Wenjing Tian,

Xinhui Pei,

Bin Zhao

Publication year - 2013

Publication title -

environmental health perspectives

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.257

H-Index - 282

eISSN - 1552-9924

pISSN - 0091-6765

DOI - 10.1289/ehp.1206066

Subject(s) - acetylcholinesterase , cholinergic , aché , aryl hydrocarbon receptor , chemistry , medicine , organophosphate , endocrinology , enzyme , biology , biochemistry , gene , pesticide , transcription factor , agronomy

Deficits in cognitive functioning have been reported in humans exposed to dioxins and dioxin-like compounds. Evidence suggests that dioxins induce cholinergic dysfunction mediated by hypothyroidism. However, little is known about direct effects of dioxins on the cholinergic system.

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