Heavy Metal Lead Exposure, Osteoporotic-like Phenotype in an Animal Model, and Depression of Wnt Signaling | Zendy

Eric E. Beier | Zendy; Jason R. Maher | Zendy; TzongJen Sheu | Zendy; Deborah A. CorySlechta | Zendy; Andrew J. Berger | Zendy; Michael J. Zuscik | Zendy; J. Edward Puzas | Zendy

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Heavy Metal Lead Exposure, Osteoporotic-like Phenotype in an Animal Model, and Depression of Wnt Signaling

Author(s) -

Eric E. Beier,

Jason R. Maher,

TzongJen Sheu,

Deborah A. CorySlechta,

Andrew J. Berger,

Michael J. Zuscik,

J. Edward Puzas

Publication year - 2012

Publication title -

environmental health perspectives

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.257

H-Index - 282

eISSN - 1552-9924

pISSN - 0091-6765

DOI - 10.1289/ehp.1205374

Subject(s) - wnt signaling pathway , bone mineral , sclerostin , medicine , adipogenesis , endocrinology , chemistry , osteoblast , osteoporosis , runx2 , stromal cell , mesenchymal stem cell , bone cell , bone remodeling , microbiology and biotechnology , signal transduction , biology , biochemistry , in vitro

Exposure to lead (Pb) from environmental and industrial sources remains an overlooked serious public health risk. Elucidating the effect of Pb on bone cell function is therefore critical for understanding its risk associated with diseases of low bone mass.

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