Time- and Dose-Related Effects of Di-(2-ethylhexyl) Phthalate and Its Main Metabolites on the Function of the Rat Fetal Testis in Vitro | Zendy

François Chauvigné | Zendy; Arnaud Menuet | Zendy; Laurianne Lesné | Zendy; MarieChristine Chag | Zendy; Cécile Chevrier | Zendy; Jean-Claude Régnier | Zendy; J. Angerer | Zendy; Bernard Jégou | Zendy

Open Access

Time- and Dose-Related Effects of Di-(2-ethylhexyl) Phthalate and Its Main Metabolites on the Function of the Rat Fetal Testis in Vitro

Author(s) -

François Chauvigné,

Arnaud Menuet,

Laurianne Lesné,

MarieChristine Chag,

Cécile Chevrier,

Jean-Claude Régnier,

J. Angerer,

Bernard Jégou

Publication year - 2008

Publication title -

environmental health perspectives

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.257

H-Index - 282

eISSN - 1552-9924

pISSN - 0091-6765

DOI - 10.1289/ehp.11870

Subject(s) - phthalate , gonocyte , medicine , sertoli cell , endocrinology , anogenital distance , fetus , metabolite , in utero , leydig cell , testosterone (patch) , biology , endocrine disruptor , endocrine system , hormone , in vitro , spermatogenesis , testicle , andrology , chemistry , luteinizing hormone , pregnancy , biochemistry , genetics , organic chemistry

Endocrine-disrupting effects of phthalates are understood primarily from in utero exposures within the fetal rat testis. Nevertheless, their path of action, dose-response character, and cellular target(s) within the fetal testis are not known.

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