Global Screening of Human Cord Blood Proteomes for Biomarkers of Toxic Exposure and Effect | Zendy

David R. Colquhoun | Zendy; Lynn R. Goldman | Zendy; Robert N. Cole | Zendy; Marjan Guček | Zendy; Malini Mansharamani | Zendy; Frank R. Witter | Zendy; Benjamin J. Apelberg | Zendy; Rolf U. Halden | Zendy

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Global Screening of Human Cord Blood Proteomes for Biomarkers of Toxic Exposure and Effect

Author(s) -

David R. Colquhoun,

Lynn R. Goldman,

Robert N. Cole,

Marjan Guček,

Malini Mansharamani,

Frank R. Witter,

Benjamin J. Apelberg,

Rolf U. Halden

Publication year - 2008

Publication title -

environmental health perspectives

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.257

H-Index - 282

eISSN - 1552-9924

pISSN - 0091-6765

DOI - 10.1289/ehp.11816

Subject(s) - in utero , proteome , cord blood , umbilical cord , physiology , proteomics , fetus , medicine , pregnancy , biomarker , biology , bioinformatics , immunology , biochemistry , genetics , gene

Exposures of pregnant women to natural and manmade chemicals can lead to negative health effects in the baby, ranging from low birth weight to developmental defects. In some cases, diseases were postulated to have their basis in toxic exposure in utero or in early childhood. Therefore, an understanding of fetal responses to environmental exposures is essential. To that end, cord blood is a readily accessible biofluid whose proteomic makeup remains mostly unexplored when compared with that of adults.

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