Open AccessElevated Human Telomerase Reverse Transcriptase Gene Expression in Blood Cells Associated with Chronic Arsenic Exposure in Inner Mongolia, China
Author(s) -
Jinyao Mo,
Yajuan Xia,
Zhixiong Ning,
Timothy J. Wade,
Judy L. Mumford
Publication year - 2008
Publication title -
environmental health perspectives
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.257
H-Index - 282
eISSN - 1552-9924
pISSN - 0091-6765
DOI - 10.1289/ehp.11532
Subject(s) - reverse transcriptase , gene expression , telomerase reverse transcriptase , gene , telomerase , arsenic , biology , polymerase chain reaction , chemistry , genetics , organic chemistry
Arsenic exposure is associated with human cancer. Telomerase-containing human telomerase reverse transcriptase (hTERT) can extend telomeres of chromosomes, delay senescence, and promote cell proliferation leading to tumorigenesis.
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