Speciation of Arsenic in Exfoliated Urinary Bladder Epithelial Cells from Individuals Exposed to Arsenic in Drinking Water
Author(s) -
Araceli HernándezZavala,
Olga L. Valenzuela,
Tomáš Matoušek,
Zuzana Drobná,
Jiřı́ Dědina,
Gonzalo G. Garcı́a-Vargas,
David J. Thomas,
Luz M. Del Razo,
Miroslav Stýblo
Publication year - 2008
Publication title -
environmental health perspectives
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.257
H-Index - 282
eISSN - 1552-9924
pISSN - 0091-6765
DOI - 10.1289/ehp.11503
Subject(s) - urine , urinary system , arsenic , chemistry , toxicity , urinary bladder , metabolite , environmental chemistry , medicine , biochemistry , organic chemistry
The concentration of arsenic in urine has been used as a marker of exposure to inorganic As (iAs). Relative proportions of urinary metabolites of iAs have been identified as potential biomarkers of susceptibility to iAs toxicity. However, the adverse effects of iAs exposure are ultimately determined by the concentrations of iAs metabolites in target tissues.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom