Deducing in Vivo Toxicity of Combustion-Derived Nanoparticles from a Cell-Free Oxidative Potency Assay and Metabolic Activation of Organic Compounds | Zendy

Tobias Stoeger | Zendy; Shinji Takenaka | Zendy; Birgit Frankenberger | Zendy; Ritter Baerbel | Zendy; Erwin Karg | Zendy; Konrad Maier | Zendy; Holger Schulz | Zendy; Otmar Schmid | Zendy

Open Access

Deducing in Vivo Toxicity of Combustion-Derived Nanoparticles from a Cell-Free Oxidative Potency Assay and Metabolic Activation of Organic Compounds

Author(s) -

Tobias Stoeger,

Shinji Takenaka,

Birgit Frankenberger,

Ritter Baerbel,

Erwin Karg,

Konrad Maier,

Holger Schulz,

Otmar Schmid

Publication year - 2008

Publication title -

environmental health perspectives

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.257

H-Index - 282

eISSN - 1552-9924

pISSN - 0091-6765

DOI - 10.1289/ehp.11370

Subject(s) - potency , oxidative phosphorylation , in vivo , chemistry , toxicity , oxidative damage , environmental chemistry , biochemistry , pharmacology , toxicology , in vitro , oxidative stress , biology , organic chemistry , microbiology and biotechnology

The inhalation of combustion-derived nanoparticles (CDNPs) is believed to cause an oxidative stress response, which in turn may lead to pulmonary or even systemic inflammation.

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